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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL15
All Species:
26.67
Human Site:
Y417
Identified Species:
65.19
UniProt:
Q96M94
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96M94
NP_085127.2
604
69775
Y417
D
P
Y
P
V
N
K
Y
G
H
E
G
T
V
L
Chimpanzee
Pan troglodytes
XP_528904
610
70498
Y423
D
P
Y
P
V
N
K
Y
G
H
E
G
T
V
L
Rhesus Macaque
Macaca mulatta
XP_001089787
604
69726
Y417
D
P
Y
P
V
N
K
Y
G
H
E
G
T
V
L
Dog
Lupus familis
XP_548897
604
69782
Y417
D
P
Y
P
V
N
K
Y
G
H
E
G
T
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPT1
617
69381
Y437
A
K
M
S
E
P
H
Y
G
H
A
G
T
V
Y
Rat
Rattus norvegicus
Q66HD2
613
69917
Y433
A
G
L
P
R
F
T
Y
G
H
A
G
T
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515542
604
69353
Y417
D
P
Y
P
V
N
K
Y
G
H
E
G
T
V
L
Chicken
Gallus gallus
Q5ZJU2
488
56640
W308
L
H
K
P
R
V
W
W
E
L
E
G
P
Q
V
Frog
Xenopus laevis
NP_001086704
240
27817
F60
S
D
Y
F
R
I
M
F
T
A
D
M
R
E
R
Zebra Danio
Brachydanio rerio
Q6DEL7
604
69488
Y417
D
P
Y
P
V
N
K
Y
G
H
E
G
T
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
99.8
99
N.A.
31.2
29.2
N.A.
90.2
75.6
35.5
85.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97
99.8
99.8
N.A.
53.3
47.3
N.A.
96
79.1
38.4
93.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
40
40
N.A.
100
20
6.6
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
40
46.6
N.A.
100
33.3
20
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
0
0
0
0
10
20
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
60
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
10
0
70
0
0
10
0
% E
% Phe:
0
0
0
10
0
10
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
80
0
0
90
0
0
0
% G
% His:
0
10
0
0
0
0
10
0
0
80
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
10
10
0
0
0
60
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
10
0
0
0
0
0
0
10
0
0
0
0
60
% L
% Met:
0
0
10
0
0
0
10
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
60
0
80
0
10
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
30
0
0
0
0
0
0
0
10
0
10
% R
% Ser:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
10
0
0
0
80
0
0
% T
% Val:
0
0
0
0
60
10
0
0
0
0
0
0
0
70
10
% V
% Trp:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
70
0
0
0
0
80
0
0
0
0
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _